Temozolomide 250mgCapsule
Anti-Cancer

Temozolomide 250mg

Temozolomide

Oral imidazotetrazine alkylating agent that spontaneously converts to the active methylating species MTIC at physiological pH, inducing O6-methylguanine DNA adducts that cause tumour cell cycle arrest and apoptosis. Combined with radiotherapy, it constitutes the Stupp protocol — the established standard of care for newly diagnosed glioblastoma multiforme since 2005. Sun Pharma and Cipla export 20mg, 100mg, and 250mg capsules widely to neuro-oncology programmes across Asia, Africa, and Latin America.

Strengths

20mg / 100mg / 250mg

Packing

5 capsules/strip

Origin

India (WHO-GMP)

MOQ

100 units

Export Price

On Request

Availability

In Stock

Quotation with pricing, availability, and shipping timeline sent within 24 hours.

Product Specifications

Composition
Temozolomide 20mg / 100mg / 250mg
Dosage Form
Capsule
Available Strengths
20mg / 100mg / 250mg
Packing
5 capsules/strip
Route of Administration
Oral, on empty stomach with water
Dosage
Concomitant phase: 75mg/m2 daily for 42 days with radiotherapy; Adjuvant: 150-200mg/m2 for 5 days per 28-day cycle
Indications
Newly diagnosed glioblastoma multiforme (with radiotherapy), refractory anaplastic astrocytoma
Country of Origin
India (WHO-GMP Certified)
Storage
Store at 25°C in a dry place
Shelf Life
24 months
Side Effects
Nausea, vomiting, constipation, headache, fatigue, thrombocytopenia, lymphopenia, seizures
Precautions
Monitor blood counts (absolute neutrophil count and platelet count); antiemetic prophylaxis recommended; pneumocystis prophylaxis for 42-day regimen; avoid in pregnancy

Disclaimer: This information is intended for healthcare professionals and international pharmaceutical buyers only. Product availability, registration status, and approved indications may vary by country. All products are supplied with Certificate of Analysis (CoA), commercial invoice, and packing list. Rx products require valid prescription in the destination country.

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